ALLICIN GARLIC'S KEY ANTIBACTERIAL COMPONENT

Recently the medical journal, Journal of Antimicrobial Agents and Chemotherapy, have confirmed the chemotherapeutic effects of GARLIC. A molecular mechanism may be the basis for some of GARLIC's therapeutic effects. The researchers were able to study how GARLIC works at the molecular level using allicin, GARLIC's main biologically active component as a model.

One study, appeared in a recent issue of The American Society for Microbiology's Antimicrobial Agents and Chemotherapy, explains how allicin fights infection. This research supports the notion that GARLIC is an excellent, although smelly, natural antimicrobial nutrient that can disable an unusually wide variety of infectious organisms.

The second study, reported in Biochimica Biophysica Acta, helps to clarify the role allicin plays in preventing heart disease and other disorders. In these studies, the scientists revealed and characterized a molecular mechanism by which allicin blocks certain groups of enzymes. Allicin, created when GARLIC cloves are crushed, protects the plant from soil parasites and fungi and is responsible for GARLIC's pungent smell.

Identified as natural weapon against infection, the research reported in Antimicrobial Agents and Chemotherapy revealed allicin disables dysentery-causing amoebas by blocking two groups of enzymes, cysteine proteinases and alcohol dehydrogenases.

Cysteine proteinase enzymes are among the main culprits in infection, providing infectious organisms with the ability to damage and invade tissues.

Alcohol dehydrogenase enzymes play a major role in these harmful organisms' metabolism and survival.

These malignant groups of enzymes are found in a wide variety of infectious organisms such as bacteria, fungi and viruses, this research provides a scientific basis for the notion that allicin is a broad-spectrum antimicrobial, capable of warding off different types of infections.

GARLIC can fight a wide range of infections and now documented studies have provided biochemical evidence for this claim. The role of allicin in warding off infection may be particularly valuable in light of the growing bacterial resistance to modern antibiotics.

It is unlikely that bacteria would develop resistance to allicin because this would require modifying the very enzymes that make their activity possible. Scientists found that allicin blocks the enzymes by reacting with one of their important components known as sulfhydryl (SH) groups, or thiols.

This finding has important implications because sulfhydryl groups are also crucial components of some enzymes that participate in the synthesis of cholesterol. By reacting with and modifying the sulfhydryl groups in those enzymes, allicin may prevent the production of artery clogging cholesterol. Suggesting that GARLIC lowers the levels of harmful cholesterol, and the study provides a possible explanation for how this may occur.

One potntial complication is the issue concerning blocking sulfhydryl groups in proteins may sometimes be harmful because these groups are also present in enzymes involved in some of the body's vital processes.

However, unlike most bacteria, human tissue cells contain detoxifying molecules of a substance called glutathione, which helps maintain appropriate sulfhydryl levels. These glutathione molecules can reverse the anti-sulfhydryl effects of small amounts of allicin.

Measuring antioxidant activity while reaction with sulfhydryl groups appears to explain most of allicin's activity, it has also been suggested allicin acts as an antioxidant. There is a study reported in BBA (We have no idea who BBA is but we agree with the reults of the study) confirming this antioxidant effect.

Antioxidants gobble up harmful free radicals believed to contribute to tumor growth, atherosclerosis, aging and other processes. Producing pure allicin in large quantities in nature, allicin is created when GARLIC cloves are cut into or crushed. The cutting or crushing causes two components of GARLIC, allciin and the enzyme allcinase, to interact.

The above information are some extracts taken from Allicin - GARLIC's Magic Bullet by Peter Josling. In this publication you will find in'depth information about allicin and all its properties. An outstanding resource we recommend you take the time to read.

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